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4,6 A key issue in the physiology of type 2 diabetes (T2DM) is the reduced incretin effect, which mainly results from decreased activity of the primary incretin hormones, GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic peptide)

doi: 10.1007/s12035-016-0170-2 430 De BellisABellastellaGPerniceVCirilloPLongoMMaioAet al

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