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Since early life adversity has the potential to modify GR methylation and transcription, adversity during childhood may lead to reduced HPA axis feedback sensitivity (Romens et al., 2015), resulting in the altered HPA axis basal activity that we find in our study

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6.3 Individual-level protective measures While environmental and regulatory interventions provide population-level protection, personalized strategies offer additional risk mitigation opportunities for individuals seeking to minimize EED exposure