A meta-analysis of 7,427 patients with Parkinson's disease showed that the prevalence of fatigue is 50%, which may be related to the hypoactivity of dopaminergic activity in the nigrostriatal pathway (17)
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Consider alternative approaches including adjuvant therapy and newer or second-generation antipsychotics such as clozapine
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Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, et al
