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The PPP is active in liver, adipose tissue, adrenal cortex, thyroid, erythrocytes, testis, and lactating mammary gland

Significant weight loss particularly reduction of visceral fat is associated with improvements in testosterone levels in men with obesity-related hypogonadism, as visceral fat drives conversion of testosterone to oestrogen

Animal studies report accelerated tissue repair and decreased scarring after injury to the reproductive tract

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Researchers investigate its role in maintaining testicular activity and fertility during testosterone-suppression states