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The body regulates B12 absorption through intrinsic factor, a protein produced in the stomach that binds to B12 and facilitates its uptake in the terminal ileum

Retrieved 9 July 2015

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demonstrated that the loss of G3PS in lipopolysaccharide-activated macrophages decreased the incorporation of [U-C]glucose into citrate 188

The signs and symptoms of this deficiency may include anemia, the buildup of too much acid in the body (metabolic acidosis), frequent infections, and symptoms caused by problems in the brain including seizures, intellectual disability, and loss of coordination (ataxia)