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In my experience, I did not see any significant skin whitening

Recent studies also show that luteolin downregulates mTOR and upregulates P53 (tumor suppressor gene).[ref][ref][ref][ref] A recent cell study on breast cancer showed that luteolin inhibited certain cancer-promoting genes

Maintaining a balanced diet, proper skincare, and healthy lifestyle habits can help support skin health even after stopping

Due to their astringent properties, tannins and other polyphenolic substances have been utilized to treat GU

This correlation does not tell us whether the symptom improvement was driven by weight loss, direct anti-inflammatory effects, or both, but it confirms that the metabolic improvements tracked alongside the symptom improvements