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Clearly, additional nutritional factors beyond vitamins, free amino acids and MSG present in the CDM are required to stimulate GABA production by L

Serotonin must be acetylated and methylated to form melatonin

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Pipecolate is further converted by pipecolic acid oxidase into piperideine-6-carboxylate (P6C), which can be spontaneously converted to AASA and enter the saccharopine pathway