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[DOI] [PubMed] [Google Scholar] 155.Kipp M., Clarner T., Dang J., Copray S., Beyer C

This study suggests that copper-coordination and ROS production might be more prevalent in intrinsically disordered proteins than realized

While even extremely high doses of GHK-Cu are unlikely to cause any adverse reactions, Pickart has estimated that the peptide can produce toxic action and start lowering a subjects blood pressure starting from an astronomical dose of about 22,500mg [13]

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 10% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof