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PD-1 inhibition in cancer patients has been linked to the gut microbiota, including Faecalibacterium, Bifidobacterium, and Akkermansia, according to several studies (Wu et al., 2009), direct DNA damage (Tsoi et al., 2017)
Failure of these treatment modalities, worsening condition or symptoms, continued loss of Meibomian glands as seen on meibography, or recurrent infections of eyelids, is highly suggestive of OMGD, a severely underdiagnosed condition
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