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When it becomes oxidized, it can break down yielding a large variety of compounds including a, -unsaturated aldehydes (Poli et al., 1987) These are toxic compounds because they can react with proteins in the cells, particularly at cysteine, lysine or histidine by either Michael addition to the carboncarbon double bond or by Schiff base formation at the carbonoxygen double bond (Esterbauer et al., 1991

10.1016/j.jconrel.2006.10.015 J

Storage temperature matters enormously for reconstituted peptides

botulinum toxin A (BONT/A) produced by the anaerobic bacterium Clostridium botulinum (153)