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Reactive metabolites from lipid peroxidation disrupt essential cellular structures, initiating cell death and DAMP releasea process further amplified by antioxidant depletion and exemplified in SLE, where neutrophils undergo ferroptosis and NETosis, activating TLR-dependent ROS generation that propagates inflammatory tissue injury (76, 87, 113115)

A recent meta-analysis of six randomized controlled trials found that supplementation with curcumin significantly reduced depression symptoms (100)

Keep sterile technique strict and refrigerate immediately after mixing

This comparison covers their structural, pharmacological, and analytical differences for laboratory research contexts

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