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Meanwhile, this condition promotes systemic inflammation, which increases the likelihood of infections, cancer, and cardiovascular incidents ( 5 Aging and kidney transplantation Human studies have revealed a notable association between the abundance of senescent cells in the kidney before transplantation and the later emergence of interstitial fibrosis, tubular atrophy, and chronic allograft nephropathy (CAN) following transplantation (Parimon et al., 2023

6B) suggesting decreased activation of oxidant-sensitive fatty acid desaturases 52