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Watanabe Y, Watanabe T, Yamaguchi Y

subsequently, secreted proteins inhibit the recruitment and infiltration of specific T-cells in tumors 57

The ideal responder profile, while biologically coherent, was identified through post hoc subgroup exploration and is vulnerable to overfitting and multiple comparison artefacts

However, under starvation cells increase production of mitochondrial-derived hydrogen peroxide, which has been shown to be partly dependent on the activation of class III PI3K (Scherz-Shouval and Elazar, 2007)