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The compound crosses the blood-brain barrier efficiently after oral administration and demonstrates sustained cognitive benefits even after treatment cessation, suggesting true structural enhancement rather than temporary stimulation

Simmons K, Thomas JV, Ludford K, Willis JA, Higbie VS, Raghav KPS, Johnson B, Dasari A, Kee BK, Parseghian CM, Lee MS, Le PH, Morelli MP, Shen JP, Bent A, Vilar E, Wolff RA, Kopetz S , Overman MJ, Morris VK

The human skin is not only an estrogen target but also a primary estrogen source

PMCID: PMC12608207

Studied together, they may accelerate the healing of injured tissue, reduce inflammation, grow muscle, spur cell regeneration, build a gut lining, and prompt new blood vessel formation