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These findings raise concerns with respect to use of L-C as a therapy or supplement in individuals with MetS

This bidirectional regulatory effect disrupts immune homeostasis and promotes the cascade amplification of inflammatory responses

[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Dong JR, Chang WW, Chen SM

Following withdrawal of NFT, Nrf2 levels rapidly declined below the detection limit, whereas GCLC levels remained significantly higher than those observed in the untreated control even after 24 h in the absence of NFT