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When the peptide is present in circulation at the time of microneedling, it amplifies the healing response and directs it toward organized collagen synthesis rather than scar formation

August 23, 2022

Nitric oxide induced by BPC 157 contributed to the promoted cell migration The in vitro angiogenic effect of BPC 157 has been shown to promote the cell migration of vascular endothelial cells in our previous study

It upregulates growth factor receptors (VEGFR2, FGFR2) and accelerates extracellular matrix remodeling in animal wound models

This is important because TNF-alpha is a driver of inflammation in IBD and a target of current therapeutics like infliximab (Remicade/Inflectra) and adalimumab (Humira)