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Blood test markers to discuss with a clinician Marker IGF-1 Why it matters Shows the downstream signal after repeated GH secretagogue activity

This work was supported in part by a KAKENHI grant from the Japan Society for the Promotion of Science [grant numbers 23K13883] (M.M.) and the Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from AMED under Grant Number JP24ama121054 (M.A.)

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Research focuses on its ability to upregulate the expression of vital tight-junction proteins (such as claudins, occludins, and zonula occludens-1), thereby minimizing luminal permeability while simultaneously boosting local mucus synthesis and stimulating vitamin D3 receptor expression