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The F/B ratio is recognized as an indicator of obesity-associated microbial dysbiosis, as confirmed in both animal and human studies 37,38

Rats were assessed for fine motoric impairment with modified Irvine, Beatties and Bresnahan forelimb scale (IBB scale) that can detect recovery of both proximal and distal forelimb function including digit movements during a naturally occurring behavior that does not require extensive training or deprivation to enhance motivation (64)

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In general, significant decreases in GSH levels (Ballatori et al., 2009) or the GSH/GSSG ratio (Sadhu et al., 2016, Zitka et al., 2012) are indicative of OS

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