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This means the B12 component in a compounded semaglutide formulation is most likely to help patients who are deficient or at risk of deficiency, those eating very little, those following plant-based diets, older adults whose B12 absorption decreases with age, or those with conditions affecting B12 absorption like gastric bypass or certain GI conditions

What happens over months and years of use matters far more for lasting health outcomes

A., Barrias, C

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No lethal dose has been established in animal studies, and the peptide appears to have wide safety margins