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Weight reduction: In the phase 2 trial, cagrilintide 4.5 mg weekly produced approximately 10.8% body weight loss over 26 weeks versus 3.0% with placebo [4]

Physical examination shows multiple facial telangiectasias, patchy vitiligo on the upper extremities, and hand sclerodactyly

Vitamin C plays a critical role in consuming oxygen and maintaining low levels of oxygen within the eye, suggesting that replenishing vitamin C in the lens and vitreous is a viable strategy for minimizing oxidative stress and reducing the risk of cataract formation

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Therefore unless the patient has a progressive neurological deficit, we can again treat them conservatively with physical therapy, chiropractic care, anti inflammatories, acupuncture, and epidural injections