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A predetermined volume of e-liquid and a built-in battery is often included with disposable vape pens

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Researchers analyzed tobacco-related toxic substances in urine samples from over 5,100 people, finding that: 17 Compared with people who had never used tobacco products , e-cigarette users had significantly higher levels of biomarkers of nicotine, tobacco-specific nitrosamines, volatile organic compounds, and metals (cadmium and lead)

Tobacco use patterns