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Because decreases in FEV 1 could be due to either bronchoconstriction and/or mucus obstruction, it is possible that dual blockade of NK1 and NK2 receptors in asthmatics augmented mucus secretion and/or bronchoconstriction to allergen

And even when an older adult has many other causes for fatigue or problems with mobility, its good to fix whatever aggravating factors such as a vitamin deficiency can be fixed

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Subsequently, a safety factor should be employed to derive the maximum recommended starting dose (MRSD) from the HED of the most relevant species