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The OptiTROP-Breast01 study demonstrates that sacituzumab tirumotecan monotherapy shows benefits in PFS and OS compared to chemotherapy in advanced TNBC
Class I ferroptosis inducers (FINs), including sorafenib, sulfasalazine, erastin, and its analog imidazole ketone erastin, inhibit system Xc-, disturb the synthesis of GSH, and subsequently deplete GSH to suppress the GPX4 enzyme activity
Was it a dietary choice, like a vegan or vegetarian diet without proper supplementation
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These may include: Nausea and stomach upset Particularly when taken on an empty stomach Diarrhoea May be more common with higher doses Loss of appetite Occasionally reported in sensitive individuals Abdominal discomfort Mild cramping or bloating Beyond digestive symptoms, some individuals report non-gastrointestinal effects such as headaches, dizziness, fatigue, or skin rashes
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