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In our recent research, it has been seen that at low concentration of 5-ALA (5 g/mL) and low irradiation energy density of 1 J/cm 2 (low-dose PDT) in both normal and diabetic cell models caused a slight increase in ROS levels compared to control groups which lead to better wound closure in those group
The Journal of clinical endocrinology and metabolism 89 , 776782, (2004)
10.1080/08923970701513443 [DOI] [PubMed] [Google Scholar] ORourke S
therefore, it is essential for these patients to undergo regular evaluation of cardiovascular parameters