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NNMT (nicotinamide N-methyltransferase) is a cytosolic enzyme that catalyzes a specific methylation reaction: it transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing two products 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine (SAH)

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Membrane Disruption & Biofilm Inhibition AMPs work by inserting into and disrupting the lipid membranes of gram-negative bacteria including the key periodontal pathogens P