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This is because the fraction of a drug that is in blood is what is distributed to the target tissue, and hence what determines the clinical action of the drug

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Suppose you have a 5 mg vial of CJC-1295 no DAC and you want to reconstitute it to achieve a standard concentration where a single application equals 100 mcg

[DOI] [PMC free article] [PubMed] [Google Scholar] 433.Chan C.W.H., Leung T.F., Choi K.C., Tsui S.K.W., Wong C.L., Chow K.M., Chan J.Y.W