oral melanotic macule histology Labial Lentigo (labial macule) Hyperpigmented macules in the oral

doi: 10.1177/0148607109353440.Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism

Oral administration of RAC--lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial

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Overuse of stimulants : Excessive use of stimulants like caffeine can exacerbate HPA axis dysfunction, while smoking and alcohol can worsen inflammation, interfere with sleep, and have other negative effects

Lloret et al