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Community Dent Oral Epidemiol

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Cholesterol, as a major component of the cell membrane, is involved in the synthesis of CoQ10 through an intermediate (isopentenyl pyrophosphate) in its synthesis pathway, thereby influencing ferroptosis

Therefore, the mechanism by which TMAO promotes the development of OA may involve promoting ferroptosis of chondrocytes

Blockade of spinal dopamine D1/D2 receptor suppresses activation of NMDA receptor through Galphaq and Src kinase to attenuate chronic bone cancer pain