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A fascinating study including over 500 patients revealed that IGF-1 concentrations were independently associated with insulin sensitivity accounting for 10.8 % of its variation

One year of insulin-like growth factor I treatment does not affect bone density, body composition, or psychological measures in postmenopausal women

Studies on stroke models in rats showed that intranasal DSIP administration led to accelerated recovery of motor functions, though brain infarction size was not significantly different from controls

However, these might be not a substitute for verification through large clinical trials

Preclinical studies suggest potential roles in soft-tissue repair, gut barrier support, angiogenesis, and neuroprotection