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doi: 10.3390/cancers14061457 63 ZhangRLiuLWangFZhaoWLiuKYuHet al

Unfortunately, vitamin C deficiency often goes undiagnosed in patients with IBD and the clinical implications have not been extensively studied

the continuous presence of glutathione throughout the day allows for diminishing the level of toxin or oxidation stress that has compromised the function of the methionine pathway

This bidirectional regulation establishes a self-perpetuating cycle where initial ferroptotic events trigger inflammatory responses, which in turn promote additional rounds of ferroptosis in surrounding tissue

It is made of three types of amino acids namely cysteine, glycine and glutamic acids