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There are anecdotal horror stories from those who purchase gray market GHK-Cu (which can cost about $50 for a months supply) and inject at home only to experience whats been dubbed the copper uglies, where your skin suddenly looks dramatically worse, as if rapidly aging instead of looking younger, like the villain who choose poorly at the end of Indiana Jones and the Last Crusade

DOI: 10.1038/s41598-017-01078-8 Casarini L & Simoni M (2018) Two Hormones for One Receptor: Evolution, Biochemistry, Actions and Pathophysiology of LH and hCG Endocr Rev 39(5):549592

Additional documented interactions include the FAK-paxillin pathway, fibroblast activity, and dopaminergic, serotonergic, and GABAergic neurotransmitter systems, though these represent a more preliminary evidence base

For patients whose deficiency is severe or accompanied by broader nutritional gaps, an IV infusion may offer advantages that a single-nutrient shot cannot match

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