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High-intensity interval training produces the most dramatic acute BDNF increase of any natural intervention

P = 1.56e-02) and IL-17 (r = -0.5359

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Furthermore, sourcing introduces uncertainty in sterility and formulation integrity, which may represent a more immediate and clinically relevant risk than theoretical biologic effects, particularly given the potential for nonsterile preparation, contamination, or inconsistent formulation in nonregulated injectable products