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Emerging alternatives, including sterile fecal filtrates and bacteriophagebased therapies may offer reduced infection risks and greater specificity, although clinical validation remains necessary [322, 323]

Surface modification with positively charged chitosan enhanced NPs binding affinity to negatively charged bacterial membranes, while PEG coating improved hydrophilicity, facilitating mucus penetration and enhancing targeted delivery, thus reducing potential copper toxicity

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Glycine-Histidine-Lysine (GHK) alleviates astrocytes injury of intracerebral hemorrhage via the Akt/miR-146a-3p/AQP4 pathway

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