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Mechanistic studies to better understand the molecular targets and pathways involved in peptide action could help identify potential adverse effects and inform safer clinical use

Triplicate measurements per sample is recommended to obtain accurate data

Do not assume the standard 21-day room temperature guideline applies to your specific formulation without confirmation

Figure 3B can provide some ideas for us to synthesize new tyrosinase inhibitory peptides

To uncover the underlying mechanisms, the researchers analyzed hippocampal tissue focusing on dentate gyrus, where they quantified neural progenitor proliferation and neurogenesis through BrdU, immunofluorescence for Sox2, GFAP, DCX and NeuN, and unbiased stereological cell counting