Some functional risk factorssuch as high blood pressure, poor glucose regulation, inactivity, smoking, and abnormal lipidscan often be improved
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358 A number of studies have indicated that the APOEe4 genotype, the best known common genetic risk factor for clinical Alzheimer's dementia, may have a stronger association with clinical Alzheimer's dementia 359 , 360 and neurodegeneration 361 in women than in men
