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Sharma A, Kumar A, Torre BGdela, Albericio F

If verified in humans, this would position epitalon not merely as a telomere compound, but as something operating at the level of epigenetic clocks the same biological machinery measured by tools like the Horvath clock to determine biological age

That's well below toxic thresholds, but chronic administration over 6+ months hasn't been studied in controlled human trials

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A 26-week diabetes study measured human activity at 1 mg, but its endpoint was blood sugar rather than long-term weight. A short outpatient cohort measured about 4.7% weight loss over four weeks at 2.5 mg. Below 1 mg, estimates rely on pharmacokinetics and mechanism