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The KruskalWallis test was used to evaluate differences in gross morphological scores, histopathological scores, and lameness duration across all four treatment groups

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At visits 1 and 5, neurocognitive assessments (Trail Making Test, Block Corsi Test, Subtest Digit Span, Category (Animal) Fluency and Controlled Oral Word Association Test, COWA (FAS test), and Rey Auditory Verbal Learning Test), collection of blood samples, measurement of abdominal circumference and body mass index (BMI) were carried out