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designed biomimetic copper/manganese silicate nanospheres (mCMSNs) to achieve GSH-eliminated synergistic therapy, where in situ GSH in tumor triggered mCMSNs biodegradation and reduced Cu 2+ into Cu + for enhanced hydroxyl radical production, leading to a powerful inhibition effect on tumors (Liu et al., 2019)

Although there can be a few valid concerns, the overall benefits of this report tend to outweigh the disadvantages