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During the 17th century, cigar manufacturers flocked to the city, bringing hundreds of Cuban and Spanish immigrants to work in their cigar factories

Gum, patch or lozenge

[61] [62] Tobacco smoke is a complex mixture of over 7,000 identified chemicals, of which 250 are known to be harmful, at least 69 cause cancer, and 98 are known to have specific toxicological properties

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"I think it's really visible how much that is happening," said Edward Woodall, ACS chief executive