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In humans, NMN doses as high as 1,200mg/day and daily NR doses up to 2,000mg have been illustrated as safe for use over a six-week period.4 31 So, a daily dose of either NMN or NR or a combination of the two up to 1,200mg should be perfectly safe for most people

Sources Phase 2 trial (NEJM) NEJM TRIUMPH-4 results Eli Lilly Related reading Retatrutide Dosage & Dosing Guide: Titration, Missed Doses, Taper Phase 3 titration schedule (246912 mg), missed-dose protocol, taper guidance, and dose-by-dose weight loss data

This is obviously prescribed off label by physicians, but keep in mind as with the other peptides in this pathway, Vilise will stimulate pigmentation

The clinical reality is usually that addressing the foundation does more than any individual ingredient on top of it