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In PCOS granulosa cells, elevated phosphorylation of the pro-apoptotic protein BAX, coupled with suppressed phosphorylation of the anti-apoptotic protein BCL-2, enhances mitochondrial pathway apoptosis, accelerating follicular atresia ( 3.6 Chronic low-grade inflammation Chronic low-grade inflammation have been identified as a central component in the pathogenesis of PCOS, rather than mere accompanying phenomena

Experimental studies suggest that the peptide may influence the secretion of hormones, and a possible mechanism of action involving the modulation of adrenergic transmission has been proposed

We find that samples with a 1:9 ratio lead to a faster recovery and relaxation, respectively, but the use of different NaOH content (Low, Medium, High) leads to very slight differences in the relaxation process (Fig

Clin Transl Med 2024;14(3):e1627