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The levels of p-STAT3 and STAT3 significantly increase, leading to overexpression of cyclooxygenase-2 (COX-2) and COX-2 mRNA, indicating that H 2 S can decrease cell apoptosis through the STAT3/COX-2 signaling pathway and promote the progression of HCC

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Hepatic histopathology of the OXA-induced ALI demonstrated varying degrees of liver cell turbidity and degeneration, even balloon like changes and focal necrosis, and sinusoidal hemorrhage in certain individuals

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Rodriguez M.L., Perez S., Mena-Molla S., Desco M.C., Ortega A.L