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Combined hormone reversal therapy (elagolix 300 mg/estradiol 1 mg/norethindrone acetate 0.5 mg) mitigated the low estrogen effect of elagolix, demonstrating superior efficacy in preventing bone density decline [161]

42 , e44 (2005)

CoQ 10 oxidoreductases in the regulation of ferroptosis (1) FSP1 in the regulation of ferroptosis FSP1 as a therapeutic target in cancer FSP1 (formerly AIFM2) was first identified as a ferroptosis regulator among CoQ 10 oxidoreductases through independent unbiased genetic screens conducted by the Conrad and Olzmann groups under conditions of GPX4 inhibition 16,17

Cells (3000/well) were seeded in 96-well plates and were incubated for 24, 48, or 72 h