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UV radiation, especially UVA and UVB, triggers ROS production in melanocytes, leading to oxidative DNA damage that can initiate oncogenic mutations

doi: 10.1016/J.CBI.2008.07.009 50 SahooDKJenaSChainyGBN

While amylin itself has a very short half-life that limits its research utility, Cag has been engineered for extended duration of action, making it a far more practical and powerful tool for studying amylin receptor signalling over longer timeframes

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Elevated MDA levels were observed in tissues collected from patients with toxic and non-toxic multinodular goitre, accompanied by reduced activity of SOD, GPx, and selenium content compared to adjacent, healthy thyroid tissue