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Suppression of acetyl-CoA acetyltransferase 1 (ACAT1) responsible for cholesterol esterification or cholesterol transporter proprotein convertase subtilisin/kexin type 9 (PCSK9) improves the anti-tumor performance of CD8 + T cells and potentiates ICB therapy (Yang et al., 2016

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Roles and regulation of the mucus barrier in the gut