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Tolerability and Safety Questions Both candidates are likely to be judged partly on gastrointestinal tolerability: nausea, vomiting, diarrhea, constipation, dose escalation, and discontinuation due to adverse events

+ - Encephalitis (en-sef-uh-LIE-tis) is inflammation of the brain

B12 is an essential vitamin that plays a role in red blood cell production, nerve function, and immune support

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However, upon binding to D -p53 TAD2 , several FOXO4-LRI residues shifted towards positive secondary chemical shifts, indicative for -helix formation (Fig