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Glutathione is readily transported across cell membranes, so that increasing circulating glutathione levels in blood would facilitate the intracellular uptake of glutathione and alleviate depleted glutathione levels observed in a variety of disease conditions

Additionally, to obtain data on the tissue expression of up- or downregulated protein in amyloid PET-positive and -negative participants, tissue expression data was downloaded from the human protein atlas 34

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Following, the cell pellets, containing a known number of cells (~ 1 10 6 cells/mL), were dissolved in 1 mL reagent: 1 N sodium hydroxide (NaOH) and 10% DMSO, and boiled at 60 C for 30 min