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Monitor patient for adverse reactions and always use under medical direction

Progressive loading protocols help tissues adapt to increasing demands while minimizing reinjury risk

A qualified clinician assesses you, selects the right needle and route, and gives the injection using single-use equipment and a clean technique, so it is quick, comfortable and safe

10.1016/0928-4257(93)90038-u 69 SikiricP.SeiwerthS.GrabarevicZ.RucmanR.PetekM.RotkvicI.et al (1993b)

It was first characterized by Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s, and a 2025 literature and patent review cataloged its effects across gastrointestinal, musculoskeletal, and neural models