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Following discovery of a sparse number of occurrences of progressive multifocal leukoencephalopathy (PML) in those taking a FAE, median duration of FAE therapy to PML symptom onset or appearance of first PML brain lesion was 31 months (range 6110), with median duration of lymphocytopenia to PML symptoms being 23 months (range 672)

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Intramuscular injection leads to faster absorption, which can increase the intensity of side effects like headaches and gastrointestinal issues

BDNF is one of the brains primary endogenous growth factors, making this a significant benchmark for Dihexas neurological activity