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For instance, this study (146) utilized a neonatal maternal separation stress model in mice to simulate irritable bowel syndrome (IBS) and identified neuronal nitric oxide synthase (nNOS) as a novel and reliable biomarker for interstitial cells of Cajal stimulation in IBS

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311 Such findings point towards different roles and different effects of reactive astrocytes at different times during the progression of autoimmune inflammation and suggest that different therapeutic approaches involving astrocytes may be required at different times

Osteoclastogenesis is upregulated due to increased expression of receptor activator of nuclear factor kappa-B ligand (RANKL) and cathepsin K, resulting in enhanced bone resorption (Table 1) (Maruotti et al., 2017)

Ascorbic Acid supports cellular functions of both the innate and adaptive immune systems